Activity (115 parameters)

automated-home-cage-based-spontaneous-behaviorIn-depth analysis of spontaneous behaviour

Mice display a variety of spontaneous behaviours in our automated home-cages (PhenoTypers), which are tracked at high resolution with video cameras. During the first three days in the PhenoTyper, our published analysis extracts 115 behavioural parameters1,2. For an initial screening of home-cage activity, we selected a set of 20 highly discriminative parameters that are representative of the total set of 115 parameters.

Comprehensive automated phenotyping

Especially when observations of spontaneous behaviour are combined with several other tests in the same cage targeting different behavioural domains, a highly detailed profile of a novel mouse mutant can be generated in a matter of a few days.

More information about data on spontaneous behaviour in automated home-cages can be found here.

1Sheltering behavior and locomotor activity in 11 genetically diverse common inbred mouse strains using home-cage monitoring. Loos et al., PLoS One. 2014; 9:e108563
2Within-strain variation in behavior differs consistently between common inbred strains of mice. Loos et al., Mamm Genome. 2015; doi: 10.1007/s00335-015-9578-7