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Loos et al. (2014) Cereb Cortex
References
|Epileptiform activity and cognitive deficits in SNAP-25(+/-) mice are normalized by antiepileptic drugs. Corradini, Loos et al., Cereb Cortex. 2014; 24:364, PMID: 23064108
Sylics starts-up a new location to expand our services and to support your CNS disease research
General
|The ongoing COVID-19 pandemic and again rising infection numbers is affecting all of us personally and our businesses. In this situation, Sylics is focused to continue and expand our support ...
Sylics stands for efficient and high quality drug screening
General
|Tight timelines? Are you in need to have a drug screening study finished before the end of the year to comply with deadlines or your annual budget? At Sylics, we ...
Relevant autism and mental retardation related changes in the Fmr1 knockout mouse
General
|In humans, the absence of the FMR1 protein leads to Fragile X syndrome, mental retardation and neurodevelopmental delays. The Fmr1 knockout mouse model is perceived as highly translational relevant due to the ...
The 22q11 mouse model available at Sylics shows robust Schizophrenia-relevant deficits
General
|Sylics characterized an accepted model in the field of schizophrenia research based on a microdeletion in the orthologous human 22q11.2 locus. In humans, a microdeletion of the 22q11.2 locus leads ...
Sylics is comitted to support CNS disease research, also during these challenging times
General
|The outbreak of COVID-19 affects all of us worldwide in an unprecedented manner. This requires us all to prioritize care and take disruptive measures to stop spread of the virus. ...
Mouse models: Alzheimer’s disease and seeding of tau pathology
General
|An Alzheimer’s Disease mouse model induced by ‘seeding’ of tau pathology may more closely mimic human tau pathology in comparison to transgenic tauopathy mouse models that overexpress human tau with ...
Recent publication: Alzheimer’s disease mouse model shows deficit in nesting behavior
Publications
|Why is nest building relevant to Alzheimer’s disease you might ask? Deterioration in the ability to perform “Activities of daily living” (ADL) is an early sign of Alzheimer’s disease. Examples ...
Sylics will attend Measuring Behavior in Manchester
Conferences
|On June 6-8, Sylics will be present at the 11th International Conference on Methods and Techniques in Behavioral Research in Manchester, United Kingdom. Manchester will be the stage for the latest inventions, ...
Updated privacy policy
General
|In order to comply with the new GDPR regulation, Sylics has updated it’s privacy statement to give a clear overview of which personal data is used for what reason. You ...
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