Sylics present at the AD/PD 2015

Sylics is represented at the 12th International Conference on Alzheimer’s and Parkinson’s Diseases that takes place in Nice from 18-22 March. We present a novel screening protocol for automated home-cages that can be used to identify behavioural changes in mouse models of Alzheimer’s disease. Recent data show that increased amyloid-β levels lead to specific age-dependent phenotypes, making it possible to distinguish between early and late consequences of amyloid-β toxicity. These results indicate that automated screening facilitates the analysis of behaviour with high sensitivity and reproducibility and can greatly contribute to research in the field of neurodegenerative disease.