Relevant autism and mental retardation related changes in the Fmr1 knockout mouse
Aug 8, 2020
Relevant autism and mental retardation related changes in the Fmr1 knockout mouse
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In humans, the absence of the FMR1 protein leads to Fragile X syndrome, mental retardation and neurodevelopmental delays. The Fmr1 knockout mouse model is perceived as highly translational relevant due to the genetic and phenotypic similarities with patients. These phenotypes make the Fmr1 KO mouse a valuable model for mental retardation and autism related drug-screening studies. If you would like to receive more information about the model or discuss a study design using this model, please reach out to us.