Publications

Recent publication: Alzheimer’s disease mouse model shows deficit in nesting behavior

Why is nest building relevant to Alzheimer’s disease you might ask? Deterioration in the ability to perform “Activities of daily living” (ADL) is an early sign of Alzheimer’s disease. Examples ...

Evidence for cognitive aging in mice using the CognitionWall protocol

In the April issue of GeroScience researchers from the University of Oklahoma Health Sciences Center (OUHSC) published a study describing the cognitive performance of aging mice using the CognitionWall protocol ...

New publication: the role of ErbB4 in attention and inhibitory control in schizophrenia

Sylics has participated in the EU funded IN-SENS Program. This has recently resulted in a publication in Genes, Brain and Behaviour on the role of the receptor tyrosine kinase ErbB4 in ...

New publication: Sylics AHCODA-DB

Our Chief Technology Officer has published a paper about AHCODA-DB, describing a public data repository of mouse phenomics data with standardized quality control and exclusion criteria aimed to enhance robustness ...

New publication: CognitionWall discrimination and reversal learning

Automation can greatly benefit standardization and efficiency of behavioural testing. Our recent paper in Learning & Memory describes the assessment of discrimination learning and cognitive flexibility without prior food restriction, extended training ...

Publications: new papers on automated screening

The LightSpot test, our automated anxiety test that enables easy and standardized screening of pharmacological compounds, is now published in Behavioural Brain Research. A second paper applied our sophisticated analysis of spontaneous behaviour in an automated ...

Publication: Novel automated operant conditioning test

Our paper describing a novel appetitive operant conditioning test for automated home-cages is accepted for publication. This test is available for our customers. Data will soon be available in our public database. A ...

Publication: Spontaneous behaviour dissected

A new publication describes the dissection of spontaneous behaviour measured in an automated home-cage into many behavioural parameters. This method facilitates a very sensitive analysis of the effects of chemical compounds and ...

Publication: Molecular mechanisms of aging-associated cognitive decline

In a collaborative project, we provide evidence for the involvement of extracellular matrix levels in impairments of spatial learning in aged mice, using the Barnes maze. Hippocampal extracellular matrix levels and ...

Publication: novel automated avoidance learning test available

In a new publication, we present a novel avoidance learning test for automated home-cages. More information about this test is available on our website. All data can be found in our public database. ...

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